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	<title>Health Products Guru &#187; Type 2 Diabetes</title>
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		<title>Kids Health Alert</title>
		<link>http://www.healthproductsguru.com/kids-health-alert/</link>
		<comments>http://www.healthproductsguru.com/kids-health-alert/#comments</comments>
		<pubDate>Mon, 21 Nov 2011 15:33:16 +0000</pubDate>
		<dc:creator>Bill Mullins</dc:creator>
				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[Boys And Girls]]></category>
		<category><![CDATA[Cardiovascular Health]]></category>
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		<category><![CDATA[Type 2 Diabetes]]></category>
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		<description><![CDATA[  This is not a drill! Parents need to step up to the plate and intervene in the lives of their children or, as predicted over a decade ago, this generation will be the first not to out live their &#8230; <a class="more-link" href="http://www.healthproductsguru.com/kids-health-alert/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
			<content:encoded><![CDATA[<h2><img class="alignnone size-full wp-image-2981" title="obesity2_0" src="http://www.healthproductsguru.com/wp-content/uploads/2011/11/obesity2_0.jpg" alt="" width="250" height="319" /><strong><span style="font-size: small;">  This is not a drill!</span></strong></h2>
<p><span style="font-size: small;">Parents need to step up to the plate and intervene in the lives of their children or, as predicted over a decade ago, this generation will be the first not to out live their parents. This is not a joke! It is not a fantasy. It is not a scare tactic. Parents had better begin to take these warnings seriously before their children pay the price for their ignorance!</span></p>
<p><span style="font-size: small;">&#8220;We are all born with ideal cardiovascular health, but right now we are looking at the loss of that health in youth,&#8221; said Donald Lloyd-Jones, M.D., chair and associate professor of preventive medicine at Northwestern University Feinberg School of Medicine and a physician at Northwestern Memorial Hospital. &#8220;Their future is bleak.&#8221; </span></p>
<p><span style="font-size: small;">The study used measurements from the AHA&#8217;s 2020 Strategic Impact Goals for monitoring cardiovascular health in adolescents and children. Among the findings:</span></p>
<p><strong>Very Poor Diets</strong>: All the 12-to-19-year-olds had terrible diets, which, surprisingly, were even worse than those of adults, Lloyd-Jones said. None of their diets met all five criteria for being healthy. Their diets were high in sodium and sugar-sweetened beverages and didn&#8217;t include enough fruits, vegetables, fiber or lean protein.</p>
<p>&#8220;They are eating too much pizza and not enough whole foods prepared inside the home, which is why their sodium is so high and fruit and vegetable content is so low,&#8221; Lloyd-Jones said.</p>
<p><strong>High Blood Sugar</strong>: More than 30 percent of boys and more than 40 percent of girls have elevated blood sugar, putting them at high risk for developing type 2 diabetes.</p>
<p><strong>Overweight or Obese</strong>: Thirty-five percent of boys and girls are overweight or obese. &#8220;These are startling rates of overweight and obesity, and we know it worsens with age,&#8221; Lloyd-Jones said. &#8220;They are off to a bad start.&#8221;</p>
<p><strong>Low Physical Activity</strong>: Approximately 38 percent of girls had an ideal physical activity level compared to 52 percent of boys.</p>
<p><strong>High Cholesterol</strong>: Girls&#8217; cholesterol levels were worse than boys&#8217;. Only 65 percent of girls met the ideal level compared to 73 percent of boys.</p>
<p><strong>Smoking</strong>: Almost 25 percent of teens had smoked within the past month of being surveyed.</p>
<p><strong>Blood Pressure</strong>: Most boys and girls (92.9 percent and 93.4 percent, respectively) had an ideal level of blood pressure.</p>
<p>The problem won&#8217;t be easy to fix. &#8220;We are much more sedentary and get less physical activity in our daily lives,&#8221; Lloyd-Jones said. &#8220;We eat more processed food, and we get less sleep. It&#8217;s a cultural phenomenon, and the many pressures on our health are moving in a bad direction. This is a big societal problem we must address.&#8221;</p>
  <a STYLE="border:none;text-decoration:none;outline:none;" href="http://www.blogform.co.cc"><img border="0" alt="HOW TO MAKE MONEY ONLINE" src="http://www.healthproductsguru.com/wp-content/plugins/related-sites-post/24x24.png"></a> <a href="http://www.blogform.co.cc/related-sites/"><strong>Related Websites</strong></a> <ul>  <li style="clear: both;"> <img  class="imgbte" hspace="5" align="left" width="100" alt="BLOGFORM" title="BLOGFORM" border=0  src="http://www.healthproductsguru.com/wp-content/plugins/related-sites-post/BTE_125x125_2.jpg"/><a onClick="window.location='http://bte.tc/cPjb'; return false;" href="http://thegardengoblin.com/because-i-can/dogs-dont-talk/">Dogs Don't Talk</a> <small>Wrote this for the kids, thought I'd post it for feedback. Once upon a time, in a land far, far away, a land that very much resembles this one, but not quite, there lived four cousins.  Well, to be specific, they were two cousins, a brother, and a sister.  Their......</small> </li> <li style="clear: both;"> <img src="http://www.weightladder.com/wp-content/uploads/2009/10/nosmoking-150x150.jpg" class="imgbte" hspace="5" align="left" width="100" alt="nosmoking" title="nosmoking" border=0><a onClick="window.location='http://bte.tc/vDW'; return false;" href="http://www.weightladder.com/more-essential-tips-for-good-health/">More Essential Tips for Good Health</a> <small>Here is a look at ten essential tips for good health, which involve diet, weight loss, good nutrition, fitness and movement and other aspects of your health. Tie these ten essential tips together and you will have a picture of good health and wellness. Essential Tip #3 - If you're......</small> </li> <li style="clear: both;"> <img src="http://www.myjourneytomillions.com/wp-content/uploads/2010/01/obamas-taxes-300x234-150x150.png" class="imgbte" hspace="5" align="left" width="100" alt="obamas taxes" title="obamas taxes" border=0><a onClick="window.location='http://bte.tc/anbM'; return false;" href="http://www.myjourneytomillions.com/articles/obamas-proposed-taxes-listed/">All of Obama's Proposed Taxes Listed (well not All because there are just too many)! </a> <small>I have never hidden my disdain for big government regardless of what political party is in charge.Â  I am a libertarian at heart, but only in moderation, of course.Â  So I got excited when I saw a post by, Executive Vice President of The Cato Institute, David Boaz, titled, â€œDemocratsâ€™......</small> </li> <li style="clear: both;"> <img src="http://www.weightladder.com/wp-content/uploads/2008/11/exercise-150x150.jpg" class="imgbte" hspace="5" align="left" width="100" alt="exercise" title="exercise" border=0><a onClick="window.location='http://bte.tc/bQy'; return false;" href="http://www.weightladder.com/are-you-skinny-fat/">Are You Skinny Fat? </a> <small>(ie: if thin people don't exercise they aren't healthy) Do you know what it means to be skinny fat? Just because you are not obviously visually overweight, that does not mean that you are healthy by any means. There are many people that appear to be thin and healthy, but......</small> </li> <li style="clear: both;"> <img src="http://www.weightladder.com/wp-content/uploads/2009/10/walking.jpg" class="imgbte" hspace="5" align="left" width="100" alt="walking" title="walking" border=0><a onClick="window.location='http://bte.tc/wYk'; return false;" href="http://www.weightladder.com/even-more-essential-tips-for-good-health/">Even More Essential Tips for Good Health</a> <small>Here is a look at ten essential tips for good health, which involve diet, weight loss, good nutrition, fitness and movement and other aspects of your health. Tie these ten essential tips together and you will have a picture of good health and wellness. Essential Tip #5 - If you......</small> </li> </ul>]]></content:encoded>
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		<title>Diabetes Drug Flaged for Cancer Risk by FDA Reviewers</title>
		<link>http://www.healthproductsguru.com/diabetes-drug-flaged-for-cancer-risk-by-fda-reviewers/</link>
		<comments>http://www.healthproductsguru.com/diabetes-drug-flaged-for-cancer-risk-by-fda-reviewers/#comments</comments>
		<pubDate>Fri, 15 Jul 2011 23:14:52 +0000</pubDate>
		<dc:creator>Bill Mullins</dc:creator>
				<category><![CDATA[Health News]]></category>
		<category><![CDATA[American Diabetes Association]]></category>
		<category><![CDATA[Bladder Cancer]]></category>
		<category><![CDATA[Bladder Cancers]]></category>
		<category><![CDATA[Breast Cancer]]></category>
		<category><![CDATA[Breast Cancers]]></category>
		<category><![CDATA[Cancer Risk]]></category>
		<category><![CDATA[Cancer Risks]]></category>
		<category><![CDATA[Dapagliflozin]]></category>
		<category><![CDATA[Diabetes Drug]]></category>
		<category><![CDATA[Fda Panel]]></category>
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		<category><![CDATA[Fda Scientists]]></category>
		<category><![CDATA[Literature Reviews]]></category>
		<category><![CDATA[Liver Toxicity]]></category>
		<category><![CDATA[Metformin]]></category>
		<category><![CDATA[Placebo Group]]></category>
		<category><![CDATA[Type 2 Diabetes]]></category>
		<category><![CDATA[Type 2 Diabetes Mellitus]]></category>
		<category><![CDATA[Walker Washington]]></category>
		<category><![CDATA[Washington Correspondent]]></category>

		<guid isPermaLink="false">http://www.healthproductsguru.com/?p=1811</guid>
		<description><![CDATA[By Emily P. Walker, Washington Correspondent, MedPage Today Published: July 15, 2011 WASHINGTON &#8212; FDA reviewers said the novel diabetes drug dapagliflozin appears effective at treating diabetes, but may pose breast and bladder cancer risks as well as liver toxicity. The &#8230; <a class="more-link" href="http://www.healthproductsguru.com/diabetes-drug-flaged-for-cancer-risk-by-fda-reviewers/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
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<td align="left">By Emily P. Walker, Washington Correspondent, MedPage Today<br />
Published: July 15, 2011</td>
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<p>WASHINGTON &#8212; FDA reviewers said the novel diabetes drug dapagliflozin appears effective at treating diabetes, but may pose breast and bladder cancer risks as well as liver toxicity.</p>
<p>The FDA&#8217;s Endocrinologic and Metabolic Advisory Committee will meet Tuesday vote whether the drug &#8212; which is the first of its kind to go before an FDA panel &#8212; should be approved as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.</p>
<p>Dapagliflozin is an inhibitor of the sodium glucose cotransporter-2 (SGLT2) which works by increasing renal glucose elimination, allowing more sugar to be excreted with urine rather than being absorbed into the bloodstream.</p>
<p>In briefing documents released Friday, FDA reviewers didn&#8217;t question the efficacy of the drug, but pointed to several safety signals.</p>
<p>Clinical trial data filed with the FDA revealed one case of bladder cancer among patients treated with 5-mg of the drug and one case of breast cancer among patients who received 10 mg. No excess cancers were observed among patients taking other doses.</p>
<p>Researchers at the <a href="http://www.medpagetoday.com/MeetingCoverage/ADA/27345" target="_blank">American Diabetes Association </a>meeting, held in late June in San Diego, reviewed the entire experience with dapagliflozin thus far and found nine bladder cancers in 5,478 patients on the drug compared with one case in 3,156 controls.They also saw nine breast cancers in 2,223 women on the drug compared with just one in 1,053 female controls.</p>
<p>The FDA reviewers pointed out that the clinical trials filed with it were not powered to detect the differences in cancer risks between dapagliflozin and the metformin/placebo group.</p>
<p>Nonetheless, the FDA scientists said their analysis of database and literature reviews suggested that the number of breast and bladder cancers in the dapagliflozin-treated group is higher than one would expect in the general type 2 diabetes population.</p>
<p>However, they stopped short of reaching any conclusions.</p>
<p>&#8220;It is uncertain whether dapagliflozin treatment is associated with an increased risk of breast cancer with the current available data,&#8221; the reviewers wrote, adding that all patients in the dapagliflozin trials should be followed to further analyze the potential breast cancer risk.</p>
<p>Tuesday&#8217;s panel will evaluate clinical trials from drugmakers Bristol-Myers Squibb and AstraZeneca that found dapagliflozin plus metformin-treated patients achieved superior glycemic control compared with patients treated with metformin plus placebo.</p>
<p>A total of 546 patients were randomized to metformin plus either placebo or one of three doses of dapagliflozin &#8212; 2.5 mg, 5 mg, or 10 mg &#8212; for 102 weeks. All dapagliflozin groups had a greater mean reduction in HbA1c and fasting plasma glucose compared with placebo. In addition, more patients achieved an HbA1c of 7% or less on the drug than on placebo (20.7% to 31.5% versus 15.4%).</p>
<p>Patients on the drug also lost a mean of 2.4 lbs., 3.8 lbs., and 3.7 lbs. &#8212; lowest to highest dose &#8212; versus an average gain of 3 lbs. for controls.</p>
<p>The efficacy of dapagliflozin is related to glucose clearance in the kidneys, so in patients with renal impairment, the drug works less well. The company is recommending that dapagliflozin should not be used in patients with moderate to severe renal impairment.</p>
<p>Because the drug causes patients to excrete more sugar, genital and bladder infections are a side effect. There were more genital infections in the drug group than in the placebo group (11.7%, 14.6%, 12.6% versus 5.1%), but urinary tract infections were similar in all groups except among those on the highest dose of dapagliflozin (about 8% versus 13%).</p>
<p>Five patients treated with dapagliflozin developed liver damage, but just one case was probably linked to the drug itself, FDA reviewers determined. The panelists will be asked about the significance of that one case and whether the drug has been evaluated enough to determined whether dapagliflozin is linked to an increased risk of hepatotoxicity</p>
<p>Tuesday&#8217;s panel will vote whether the dapagliflozin is safe and effective. The FDA is not required to follow the advice of its advisory panels, but it often does.</p>
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		<title>Vitamin D Deficiency Is Associated With Different Types of Obesity in Black and White Children</title>
		<link>http://www.healthproductsguru.com/vitamin-d-deficiency-is-associated-with-different-types-of-obesity-in-black-and-white-children/</link>
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		<pubDate>Thu, 23 Jun 2011 06:51:49 +0000</pubDate>
		<dc:creator>Bill Mullins</dc:creator>
				<category><![CDATA[Children]]></category>
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		<category><![CDATA[June 21]]></category>
		<category><![CDATA[Lipid Levels]]></category>
		<category><![CDATA[Metabolism]]></category>
		<category><![CDATA[Obesity Children]]></category>
		<category><![CDATA[Racial Differences]]></category>
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		<category><![CDATA[University Of Pittsburgh]]></category>
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		<category><![CDATA[Vitamin D Deficiency]]></category>

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		<description><![CDATA[ScienceDaily (June 21, 2011) — A recent study accepted for publication in The Endocrine Society&#8217;s Journal of Clinical Endocrinology &#38; Metabolism (JCEM) found that while black and white children with vitamin D deficiency both had higher fat levels, black children &#8230; <a class="more-link" href="http://www.healthproductsguru.com/vitamin-d-deficiency-is-associated-with-different-types-of-obesity-in-black-and-white-children/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
			<content:encoded><![CDATA[<p>ScienceDaily (June 21, 2011) — A recent study accepted for publication in The Endocrine Society&#8217;s <em>Journal of Clinical Endocrinology &amp; Metabolism</em> (JCEM) found that while black and white children with vitamin D  deficiency both had higher fat levels, black children were more likely  to have higher levels of fat just under their skin and white children  were more likely to have higher levels of fat between their internal  organs.</p>
<p>Studies in adults and children have shown a link between obesity and  vitamin D deficiency. However, data characterizing the racial  differences in the relationship between obesity and vitamin D,  particularly in fat tissue distribution are limited. This study examined  the racial differences in the relationship between vitamin D status,  BMI, fat levels, fat distribution and lipid levels in healthy obese and  non-obese 8-18 year old black and white children.</p>
<p>&#8220;Vitamin D deficiency is rampant in American youth, and there is some  suggestion in adults that low levels of vitamin D may be playing a role  in the increasing rates of type 2 diabetes. It is possible the same may  be true for youth with type 2 diabetes,&#8221; said Silva Arslanian, MD, of  the University of Pittsburgh and lead author of the study. &#8220;Our study  found that vitamin D was associated with higher fat levels and lower  levels of high-density lipoprotein (HDL), also known as good  cholesterol, in both black and white children.&#8221;</p>
<p>In this study, researchers measured vitamin D levels in 237 children  and found the majority of the study participants were vitamin D  deficient. Plasma vitamin D levels were associated inversely with BMI  and fat levels and positively with HDL cholesterol in all subjects.  Visceral adipose tissue (fat between internal organs) was higher in  vitamin D deficient whites and subcutaneous adipose tissue (fat below  the skin) was higher in vitamin D deficient blacks compared with their  respective vitamin D non-deficient counterparts.</p>
<p>&#8220;Besides therapeutic interventions to correct the high rates of  vitamin D deficiency in youth, benefits of vitamin D optimization on fat  levels, lipid profile and risk of type 2 diabetes need to be explored,&#8221;  said Arslanian.</p>
<p>Other researchers working on the study include: Kumaravel Rajakumar,  Javier de las Heras and SoJung Lee of the University of Pittsburgh in  Penn.; and Tai Chen and Michael Holick of Boston University in Mass.</p>
<p><span style="color: #ffffff;">-</span></p>
<p>Journal Reference:</p>
<ol>
<li>L. George, F. Bacha, S. Lee, H. Tfayli, E. Andreatta, S. Arslanian. Surrogate  Estimates of Insulin Sensitivity in Obese Youth Along the Spectrum of  Glucose Tolerance from Normal to Prediabetes to Diabetes. <em>Journal of Clinical Endocrinology &amp; Metabolism</em>, 2011; DOI: <a rel="nofollow" href="http://dx.doi.org/10.1210/jc.2010-2813" target="_blank">10.1210/jc.2010-2813</a></li>
</ol>
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		<title>Is Vitamin D supplementation necessary?</title>
		<link>http://www.healthproductsguru.com/is-vitamin-d-supplementation-necessary/</link>
		<comments>http://www.healthproductsguru.com/is-vitamin-d-supplementation-necessary/#comments</comments>
		<pubDate>Fri, 24 Jul 2009 17:07:05 +0000</pubDate>
		<dc:creator>Bill Mullins</dc:creator>
				<category><![CDATA[Editorial]]></category>
		<category><![CDATA[Elements of Health]]></category>
		<category><![CDATA[Natural Remedies]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[American Journal Of Clinical Nutrition]]></category>
		<category><![CDATA[American Journal Of Clinical Nutrition March 2007]]></category>
		<category><![CDATA[Biological Medicine]]></category>
		<category><![CDATA[Cancer Risk]]></category>
		<category><![CDATA[Hypertension]]></category>
		<category><![CDATA[Immune System]]></category>
		<category><![CDATA[Intestinal Tract]]></category>
		<category><![CDATA[Journal Of Clinical Nutrition]]></category>
		<category><![CDATA[Michael Holick]]></category>
		<category><![CDATA[Mineralization]]></category>
		<category><![CDATA[Murdoch University School]]></category>
		<category><![CDATA[Nutrition Experts]]></category>
		<category><![CDATA[Phosphorus]]></category>
		<category><![CDATA[Radiation Exposure]]></category>
		<category><![CDATA[Source Of Vitamin D]]></category>
		<category><![CDATA[Sun Exposure]]></category>
		<category><![CDATA[Trevor Marshall]]></category>
		<category><![CDATA[Type 2 Diabetes]]></category>
		<category><![CDATA[Ultraviolet Rays]]></category>
		<category><![CDATA[Uv Radiation]]></category>

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		<description><![CDATA[We all know that the presence of vitamin D in our bodies is important for a variety of reasons notably for the absorption and utilization of calcium &#38; phosphorus by the intestinal tract, to enable normal mineralization of the bone, &#8230; <a class="more-link" href="http://www.healthproductsguru.com/is-vitamin-d-supplementation-necessary/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
			<content:encoded><![CDATA[<p><img class="alignnone size-full wp-image-150" title="Vitamin-D_Sun" src="http://www.healthproductsguru.com/wp-content/uploads/2009/07/Vitamin-D_Sun.jpg" alt="Vitamin-D_Sun" width="244" height="244" /></p>
<p>We all know that the presence of vitamin D in our bodies is important for a variety of reasons notably for the absorption and utilization of calcium &amp; phosphorus by the intestinal tract, to enable normal mineralization of the bone, reduce cancer risk and may play a role in the prevention or treatment of type 1 and type 2 diabetes, hypertension and multiple sclerosis.</p>
<p>The question here is what is the best source of vitamin D?</p>
<p>Science seems to be divided on the answer to this question especially in the area of supplementation.  There are some scientists who believe that our diets are deficient in vitamin D and that supplementation is necessary.  Others say that the recommended dosages for adequate vitamin D supplementation are inadequate (Michael Holick, M.D., and a group of other nutrition experts writing in the American Journal of Clinical Nutrition (March, 2007, 85(3);649-650.)  Still others claim that vitamin D supplementation suppresses the immune system (Trevor Marshall, Ph.D., professor at Australia’s Murdoch University School of Biological Medicine and Biotechnology).</p>
<p>In the absence of a clear scientific conclusion where should we turn for the answer to the question at hand?   Personally, when I am conflicted, having no clear choice I always chose to err on the side of safety and turn to the body&#8217;s built in mechanisms.  The body produces vitamin D naturally when the skin is exposed to ultraviolet rays.  In my opinion this is the most natural method of assuring that vitamin D is present in the body.  Many studies show that most people meet their vitamin D needs through exposure to sunlight.  The factors that affect UV radiation exposure and research to date on the amount of sun exposure needed to maintain adequate vitamin D levels make it difficult to provide general guidelines. It has been suggested by some vitamin D researchers, for example, that approximately 5-30 minutes of sun exposure between 10 AM and 3 PM at least twice a week to the face, arms, legs, or back without sunscreen usually lead to sufficient vitamin D synthesis and that the moderate use of commercial tanning beds that emit 2-6% UVB radiation is also effective.  Individuals with limited sun exposure need to include good sources of vitamin D in their diet (milk or fish) or take a supplement.</p>
<p>It is important to note that vitamin D obtained from sun exposure, food, and supplements is biologically inert and must undergo two hydroxylations in the body for activation. The first occurs in the liver and converts vitamin D to 25-hydroxyvitamin D [25(OH)D], also known as calcidiol. The second occurs primarily in the kidney and forms the physiologically active 1,25-dihydroxyvitamin D [1,25(OH)2D], also known as clairol.  For people who suffer from some kind of dysfunction of the liver or kidney further supplementation may be necessary for the body to hydroxylate the vitimin.  If you do suffer from inadequate liver or kidney function and desire to optimize the way your body uses vitamin D you should consult your physician.</p>
<p>Conclusion:  Until there is a clear consensus on weather vitamin D supplementation is beneficial or harmful I suggest letting your body  produce it’s own vitamin D from sunlight as it was designed to do.</p>
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