Studies have shown that Fucoidan helps to activate dendritic cells within the body.  These dendritic cells have been shown to be the most effective anitigen presenting cells for naïve T-cells and initiates the process of immune system recognition of a new pathogen.

In simple terms dendritic cells help the body to identify new invaders and pass the information on to helper T-cells, killer T-cells and B cells (which all fight pathogens such as bacteria and viruses).  Dendritic cells are derived from hemopoietic bone marrow progenitor cells.  These progenitor cells initially transform into immature dendritic cells.  These immature dendritic cells, through the use of pattern recognition receptors, are constantly sampling their surrounding areas for pathogens.  Once these specialized cells come into contact with a pathogen they, through a process called “nibbling” basically take samples of the pathogen, degrade their proteins into small pieces and present those fragments at their cell surface.

Simultaneously, they upregulate cell-surface receptors that act as co-receptors in T-cell activation such as CD80 (B7.1), CD86 (B7.2), and CD40 greatly enhancing their ability to activate T-cells. They also upregulate CCR7, a chemotactic receptor that induces the dendritic cell to travel through the blood stream to the spleen or through the lymphatic system to a lymph node. Here they act as antigen-presenting cells: they activate helper T-cells and killer T-cells as well as B-cells by presenting them with antigens derived from the pathogen, alongside non-antigen specific costimulatory signals.

This, simply stated sets the immune system into motion.  The “helper T-Cells (Th)” for all intents and purposes are the traffic cops of the immune system.  Th cells are involved in activating and directing other immune cells, and are particularly important in the immune system. They are essential in determining B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages. It is this diversity in function and their role in influencing other cells that gives T helper cells their name.

Killer T-Cells are a type of T cell that attacks cells having specific antigens on their surface, such as cancer cells or cells infected with a virus. Also called cytotoxic T cell or CD8+ T cell.

The principal functions of B cells are to make antibodies against antigens, perform the role of Antigen Presenting Cells (APCs) and eventually develop into memory B cells after activation by antigen interaction. B cells are an essential component of the adaptive immune system.

Understanding how the immune system works and how Fucoidan sets the wheels in motion gives us a clear picture as to the potential that this important sea-derived substance may be the natural answer to H1N1 that we have all been looking for.

For information about the pure Fucoidan functional beverage Zradical  Click Here.

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Oradical is a superior liquid super antioxidant beverage from the Xymetri product line.  Oradical combines centuries of herbal knowledge with intensive modern scientific study resulting in a formula that will provide vital nutrients along with stimulating and regulating factors from plants, all in a highly concentrated liquid form.

As we all know antioxidants are critical in neutralizing free radicals that ravage our bodies.  Free radicals are known to cause damage to our chromosomes, they destroy enzymes and they even disrupt cell membranes.  Everything that happens in our bodies begins at the cellular level. And the cell membrane regulates what passes into and out of our cells namely nutrients and waste products.  It is impossible for us to maintain optimal health when these free radicals are permitted to go unchecked and damage our cells.  Free radicals enter our bodies primarily from the foods that we eat, the water we drink and the air that we breath.  They effect our immune system and make us susceptible to viruses and bacteria.  They can destroy blood vessels and contribute to cardio vascular disease.  Free radicals can also cause genetic damage and cause cancer.

Antioxidants are commonly found  in fruits and vegetables.  The problem is that the fruits and vegetables that we consume are antioxidant deficient.  Even if we consume these products in their raw form, thus preventing the destruction of these critical nutrients from heat, we are still not getting the antioxidants that we need in our bodies.  The problem with our fruits and vegetables is that they are grown in depleted soils and are nutritionally deficient (US Senate document 264 states that some 90% of our population is deficient of nutrients due to depleted soil).  It is for this reason that people are actually beginning to age prematurely.  This fact accounts for the increase in diseases that used to be attributed to aging now being found in younger people.

In an attempt to combat this trend a new industry has been born and is called the Functional Beverage Industry.  This industry was designed to protect us from the damage caused by free radicals.  Naturally, with any new industry, there are companies out there making hundreds of millions of dollars producing and marketing these antioxidant beverages.  The question is, of all of the products on the market, which one is the best one for you?

The scientific community has come up with a way to accurately measure the ability of fruits and vegetables to stop the effects of free radicals.  This bench mark, so to speak is called an Oxygen Radical Absorbance Capacity Score (ORAC Score).  The higher the ORAC Score the greater the potential to eliminate free radicals.  The standard set by the scientists who developed  this ORAC scoring system have determined that about 5000 ORAC units score per/day  is the goal to protect our bodies.  The Food and Drug Administration (FDA) recommends that we increase our ORAC Scores to these levels to stay healthy.

Oradical is one of the most potent antioxidant functional beverages available today (161,000 ORAC Score per/bottle – evaluated by Brunswick Labs).  Not only is it made from the finest materials it is also the most cost effective.  To reach the values per/day. as recommended by the FDA, ZanGo would cost you about $90 per/month and Noni about $300 per month.  What is the cost of Oradical?  $40.00 per/month!  What makes oradical a superior product?  All you need to do is see the list of ingredients.  Oradical incorporates the most powerful antioxidants known to man in one great tasting fruit juice.  Some of these ingredients are alo vera leaf extract, grape skin extract, acai fruit extract, mangosteen fruit extract, raspberry juice concentrate, green tea leaf extract, cherry juice concentrate, purified water, (fructose), natural flavors – NO HARMFUL PRESERVATIVES!!!

You must try this product.  You will be glad you did!

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Zradical – Is the only liquid beverage on the market with pure fucoidan using a proprietary cold water vaccum extraction, Zradical supports the immune system, helps joint function, improves healthy cell maintenance.

About 4 percent of the total dry weight of many types of brown seaweed consists of a polysaccharide known as Fucoidan.  Fucoidan is a sulfated polysaccharide that possesses a complex structure.  Its chief components include a sulfuric esterified L-fucose, and the trace elements of galactose, xylose, and glucuronic acid.

Japanese researchers discovered that a polysaccharide known as Fucoidan found in kombu and other types of brown seaweed (wakame, mozuku, and hijiki), causes various types of established cancer cell lines to self-destruct.  Examples of cancer cell strains where this self-destruct phenomenon was observed include human acute promyelocytic leukemia cells (HL-60 cell line), human stomach cancer cells (AGS cell line), human colon cancer cells (HCT-116 cell line), and cancer cells of the descending colon (SW-480 cell line/WiDr cell line).  Moreover, this self-destruction was observed to take place without affecting normal cells.  Currently, efforts are underway to clarify the precise mechanism by which this phenomenon occurs.

From ancient times (dating from the Jomon era, approximately before the 2nd Century BC onwards), brown seaweed has been a mainstay of the traditional Japanese diet.  The inhabitants of Okinawa, Japan enjoy some of the highest life expectancies in Japan.  Okinawans happen to have one of the highest per capita consumption rates of kombu — 1 gram per person per day.  It is noteworthy that the cancer death rate in Okinawa is the lowest of all the prefectures in Japan.

The average per capita consumption rate of kombu in Japan is approximately 0.5 grams per day.  Such a serving of kombu would include roughly 5 mg of Fucoidan.  In vivo experiments are currently underway to determine the effects of Fucoidan within living organisms.  If it is confirmed that Fucoidan can help bring about apoptosis solely in cancer cells that are multiplying at uncontrolled rates, we would then have within our reach the long-dreamed-of cancer drug — one that does its job without causing adverse side effects.

1. Hepatology Research, Volume 35, Issue 3, Pages 190-198
A. Saito, M. Yoneda, S. Yokohama, M. Okada, M. Haneda, K. Nakamura

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